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1.
Acta sci. vet. (Impr.) ; 49: Pub. 1841, 2021. tab
Article in English | LILACS, VETINDEX | ID: biblio-1363601

ABSTRACT

Capybaras have found favorable conditions for survival and reproduction in green urban environments. In recent years, the population of these large rodents has been increasingly abundant in several brazilian cities such as Uberlândia, a municipality of the southeastern region with a Cerrado biome. Capybaras are important in the Brazilian Spotted Fever epidemiological chain, by amplifying infection rates of the vector population. However, knowledge of this host's physiology is scarce. Thus, the aim of this work was to describe hematological and biochemical parameters of free-living capybaras groups in urbanized areas in the city of Uberlândia, Minas Gerais State, Brazil. Capybaras were captured in 4 different locations of Uberlândia city, Minas Gerais state, including 1 Condominium (P1), 1 Private Market Garden (P2), 1 Private Club (P3) and 1 Municipal Park (P4). The animals were baited into an octagonal iron corral and chemically contained with anesthetic darts. After sedated, blood was collected from the femoral vein in tubes with and without EDTA. Biochemical evaluation, hematological analysis with differential leukocyte counts and search for Dirofilaria sp. were done. The blood count and biochemistry values obtained from animals of different ages, sex and sectors (P1, P2, P3 and P4) were submitted to the Shapiro-Wilk normality test, considering 95% significance. Values that had a normal distribution were subjected to ANOVA tests followed by Student's t-test. Values that did not follow normality were submitted to the Kruskal-Wallis test, to obtain a P-value, with a significance level of 95%. A total of 19 capybaras were captured: 4 in P1, 6 in P2, 4 in P3 and 5 in P4. From the 19 animals, 13 were females (68.42%) and 6 were males (31.57%), 12 adults (63.15%) and 7 juveniles (36.84%). Apart from occasional skin scars and moderate to intense Ambyomma spp. tick infestations, all captured animals were healthy on a broad examination. From 5 animals captured in P4, despite the use of anticoagulant, blood from 4 animals clotted fast. No microfilariae were found in the thick drop test in any of the 19 animals sampled, and in 2 adult female capybaras captured in P1, Kurloff cells were observed. Hematological and biochemical values presented no major differences when comparing sex and age. Nevertheless, differences in liver and kidney profile were observed between the capybara groups, including ALT, alkaline phosphorus, BUN and creatinine. Blood from 4 animals clotted fast, despite the use of EDTA tubes. Blood clotting of samples with anticoagulant in this work could be associated with some physiological features inherent to capybaras. Many attempts were required to obtain enough blood from each individual due to the rapid hemostasis, what come in accordance with reports in literature. Kurloff cells were observed in 2 adult female capybaras captured in P1, which can be found in peripheral blood of female rodents during follicular phase of estrous cycle. Hematological and biochemical values differences in liver enzymes such as ALT and alkaline phosphorus, and kidney profile enzymes including BUN and creatinine could be associated to capture stress or dietetic variation between groups. Despite statistical relevant, the values were still in accordance with other works, although comparisons should be done with caution since various environments exert a diverse array of stimulus upon the animals such as parasitic, infective, stress, nutritional, social and undoubtedly blood parameters mirror them. In conclusion, this work contributes to the standardization of free-living capybaras' physiological parameters in urban areas.(AU)


Subject(s)
Animals , Rickettsia rickettsii , Rodentia/physiology , Rodentia/blood , Tick Infestations/epidemiology , Rocky Mountain Spotted Fever/epidemiology
2.
Arq. bras. med. vet. zootec. (Online) ; 72(2): 461-470, Mar./Apr. 2020. tab
Article in Portuguese | LILACS, VETINDEX | ID: biblio-1128377

ABSTRACT

Devido à ausência de estudos sobre capivaras na região Nordeste do Brasil, o objetivo deste estudo foi avaliar a sanidade desses roedores de vida livre em três áreas dos biomas Mata Atlântica (2) e Caatinga (1) do estado de Pernambuco, por meio da determinação de parâmetros da hematologia e bioquímica sérica. De novembro de 2016 a dezembro de 2017, foram capturados 21 animais, dos quais foram coletadas amostras de sangue para avaliação hematológica (eritrograma, leucograma e plaquetometria) e bioquímica sérica (atividade enzimática, perfil proteico, energético e mineral). A maioria dos parâmetros esteve dentro dos valores de normalidade para a espécie, embora alguns apresentassem diferenças estatisticamente significativas de acordo com a área de estudo (hemoglobina, hematócrito, VCM, CHCM, eosinófilos, fosfatase alcalina, proteína total, albumina, ácido úrico, creatinina, lactato, sódio e magnésio) e o sexo dos animais (ácido úrico). Os parâmetros obtidos são apresentados como referência e atestam a sanidade e o bom estado nutricional de populações de capivaras nos biomas Mata Atlântica e Caatinga da região Nordeste do Brasil. As informações aportadas neste estudo pioneiro na região Nordeste contribuem para aumentar o conhecimento sobre a ecofisiologia e a conservação in situ de capivaras.(AU)


Due to the lack of studies about capybaras in the northeast region of Brazil, the objective of this study was to evaluate the health status of free-ranging capybaras in three areas of Atlantic Forest (2) and Caatinga (1) biomes in Pernambuco state, through the determination of hematological and serum biochemical parameters. From November 2016 to December 2017, 21 animals were captured and blood samples were collected for the hematological (erythrogram, leukogram and platelet counts) and serum biochemistry (enzymatic activity, protein, energy and mineral profile) evaluation. Hematological and serum biochemical parameters were within the normal range for the species, but some presented statistically significant variations according to the study area (hemoglobin, hematocrit, MCV, MCHC, eosinophils count, alkaline phosphatase, total proteins, albumin, uric acid, creatinine, lactate, sodium and magnesium) and sex of the animals (uric acid). The parameters obtained are presented as reference and attest to the health and good nutritional status of populations of capybaras in the Atlantic Forest and Caatinga biomes of northeastern Brazil. The information provided in this pioneering study in the northeast region contributes to increased knowledge about the ecophysiology and in situ conservation of capybaras.(AU)


Subject(s)
Animals , Rodentia/blood , Biochemical Phenomena , Ecosystem , /methods , Hematologic Tests/veterinary
3.
Mem. Inst. Oswaldo Cruz ; 109(7): 899-904, 11/2014. tab, graf
Article in English | LILACS | ID: lil-728808

ABSTRACT

Visceral leishmaniasis (VL) in Brazil is transmitted by the phlebotomine Lutzomyia longipalpis and in some midwestern regions by Lutzomyia cruzi. Studies of the phlebotomine fauna, feeding habits and natural infection rate by Leishmania contribute to increased understanding of the epidemiological chain of leishmaniases and their vectorial capacity. Collections were performed in Jaciara, state of Mato Grosso from 2010-2013, during which time 2,011 phlebotomines (23 species) were captured (68.70% Lu. cruzi and 20.52% Lutzomyia whitmani). Lu. cruzi females were identified by observing the shapes of the cibarium (a portion of the mouthpart) and spermatheca, from which samples were obtained for polymerase chain reaction to determine the rates of natural infection. Engorged phlebotomines were assessed to identify the blood-meal host by ELISA. A moderate correlation was discovered between the number of Lu. cruzi and the temperature and the minimum rate of infection was 6.10%. Twenty-two females were reactive to the antisera of bird (28%), dog (3.30%) and skunk (1.60%). We conclude that Lu. cruzi and Lu. whitmani have adapted to the urban environment in this region and that Lu. cruzi is the most likely vector of VL in Jaciara. Moreover, maintenance of Leishmania in the environment is likely aided by the presence of birds and domestic and synanthropic animals.


Subject(s)
Animals , Dogs , Humans , DNA, Protozoan/isolation & purification , Insect Vectors/parasitology , Leishmania/genetics , Leishmaniasis, Visceral/transmission , Psychodidae/classification , Biodiversity , Brazil , Birds/blood , Enzyme-Linked Immunosorbent Assay , Feeding Behavior/physiology , Grassland , Immune Sera , Insect Vectors/pathogenicity , Leishmaniasis, Visceral/parasitology , Mephitidae/blood , Polymerase Chain Reaction , Psychodidae/parasitology , Psychodidae/pathogenicity , Rodentia/blood , Weather
4.
Rev. bras. parasitol. vet ; 22(4): 519-524, Oct.-Dec. 2013. tab, ilus
Article in English | LILACS, VETINDEX | ID: lil-698025

ABSTRACT

The South American water rat Nectomys squamipes is a wild mammal reservoir of Schistosoma mansoni in Brazil. In the present study, wild rodents were collected in the field and categorized into two groups: infected and uninfected by S. mansoni. Blood was collected to analyze changes in the serum glucose level (mg/dL) and liver fragments were used to determine the hepatic glycogen content (mg of glucose/g tissue). The histological examination showed inflammatory granulomatous lesions in different phases of development in the liver of rodents naturally infected with S. mansoni, in some cases with total or partial occlusion of the vascular lumen. Early lesions were characterized by the presence of inflammatory infiltrate around morphologically intact recently deposited eggs. Despite the significance of these histological lesions, the biochemical changes differed in extent. N. squamipes naturally infected by S. mansoni showed no variation in hepatic glycogen reserves. These findings were accompanied by a significant increase in plasma glucose contents, probably as a consequence of amino acids deamination, which are degraded, resulting in the formation of intermediates used as precursors for the glucose formation, without compromising the reserves of liver glycogen. In the wild, naturally infected N. squamipes can maintain S. mansoni infections without undergoing alterations in its carbohydrate metabolism, which minimizes the deleterious effects of S. mansoni.


Nectomys squamipes é um mamífero silvestre reservatório de Schistosoma mansoni no Brasil. No presente estudo, os roedores silvestres, colhidos no campo, foram classificados em dois grupos: infectado e não infectado por S. mansoni. O sangue foi colhido para análise da alteração no nível de glicose sérico (mg/dL) e fragmentos de fígado foram usados para determinar o conteúdo de glicogênio hepático (mg de glicose/g tecido). A análise histológica demonstrou lesões granulomatosas em diferentes fases de desenvolvimento no tecido hepático dos roedores naturalmente infectados com S. mansoni, localizados principalmente na região periportal, com total ou parcial oclusão do lúmen vascular. As lesões foram caracterizadas por presença de infiltrado inflamatório ao redor de ovos morfologicamente intactos recentemente depositados. Apesar da grande significância das lesões histológicas, as alterações bioquímicas não diferiram no mesmo grau. N. squamipes naturalmente por S. mansoni não apresentaram variação na reserva de glicogênio hepático. Esses achados foram acompanhados pelo aumento significativo nos conteúdos de glicose plasmática, provavelmente como consequência ao processo desaminativo de aminoácidos, que passam a ser degradados notadamente para a formação de glucose, sem contudo comprometer a reserva de glicogênio hepático. Em condições naturais a infecção de S. mansoni pode ser mantida usando N. squamipes como hospedeiro definitivo, sem alterações significativas nos conteúdos de glicogênio hepático, minimizando os efeitos deletérios causados por S. mansoni nos roedores N. squamipes naturalmente infectados.


Subject(s)
Animals , Male , Female , Rodentia/blood , Liver/metabolism , Liver/pathology , Rodentia/parasitology , Schistosoma mansoni/isolation & purification , Schistosomiasis mansoni/veterinary , Liver/parasitology , Schistosomiasis mansoni/metabolism , Schistosomiasis mansoni/pathology
5.
Biomédica (Bogotá) ; 33(supl.1): 38-51, set. 2013. ilus, graf, tab
Article in Spanish | LILACS | ID: lil-695795

ABSTRACT

Introducción. Las rickettsias son bacterias patógenas usualmente transmitidas por ectoparásitos, como garrapatas, piojos o pulgas. En la última década se presentaron tres brotes de rickettsiosis con casos fatales en la región noroccidental de Antioquia y en un municipio limítrofe de Córdoba. Objetivo. Describir la ecología y la epidemiología de las infecciones por Rickettsia spp. en el Urabá antioqueño. Materiales y métodos. Se obtuvieron muestras de 354 roedores y se recolectaron 839 ectoparásitos de estos en los municipios de Apartadó, Turbo y Necoclí. Asimismo, se obtuvieron 220 sueros humanos. Estas muestras fueron estudiadas por reacción en cadena de la polimerasa (PCR) e inmunofluorescencia indirecta (IFI) para la detección de infección por rickettsias. Resultados. Por IFI se detectaron anticuerpos antirickettsias en 130 (43 %) de los roedores y en 53 (24 %) de los sueros humanos estudiados. Además, se amplificaron secuencias del gen gltA específicas del género Rickettsia en 23 (6,8 %) muestras de hígado de roedores, las cuales mostraron una similitud del 98,7 % con R. prowazekii . Una secuencia de gltA obtenida de larvas de garrapatas del género Amblyomma sp., tuvo una identidad mayor de 99 % con las secuencias de R. tamurae . Conclusión. Estos resultados demuestran la circulación de rickettsias en roedores, ectoparásitos y humanos en los municipios estudiados.


Introduction: Rickettsia spp. are tick, flea or lice-borne pathogenic bacterium, usually carried by rodents. In the last decade three outbreaks of rickettsial disease including fatalities, occurred in the provinces of Antioquia and Córdoba in northwestern Colombia. Objective: The purpose of this study was to perform an ecological and epidemiological description of the Rickettsia spp infection in the recently affected region of Colombia. Materials and methods: Samples were obtained from 354 rodents and their parasites captured in the municipalities of Apartadó, Turbo and Necoclí. Likewise, 220 human sera were also collected, for detection of infection by Rickettsia spp. Results: Indirect immunofluorescence assay (IFA) revealed that 130 (43%) of the rodents and 53 (24%) of the humans produced antibodies to Rickettsia spp. Additionally, rickettsial DNA was amplified by PCR from 23 (6.8%) rodent liver samples using primers directed to the genus specific gltA gene. While gltA sequences from rodent samples exhibited a 98.7% similitude with R . prowazekii, a sequence amplified from larvae of Amblyomma sp exhibited identities of >99% similarity with R. tamurae . Conclusion: These results demonstrate the presence of rickettsia in rodents, ectoparasites and humans throughout the municipalities studied.


Subject(s)
Adult , Animals , Child , Female , Humans , Male , Middle Aged , Antibodies, Bacterial/blood , Arachnid Vectors/microbiology , Disease Reservoirs/parasitology , Rickettsia Infections/epidemiology , Rickettsia/isolation & purification , Rodentia/parasitology , Tick Infestations/veterinary , Colombia/epidemiology , Disease Outbreaks , Endemic Diseases , Immunoglobulin G/blood , Immunoglobulin G/immunology , Larva/microbiology , Liver/microbiology , Mites/microbiology , Phylogeny , Rickettsia Infections/blood , Rickettsia Infections/transmission , Rickettsia Infections/veterinary , Rickettsia/genetics , Rickettsia/immunology , Rodentia/blood , Seroepidemiologic Studies , Socioeconomic Factors , Tick Infestations/epidemiology , Ticks/microbiology
6.
Rev. biol. trop ; 59(1): 29-35, mar. 2011. graf, tab
Article in English | LILACS | ID: lil-638043

ABSTRACT

Plasma concentration of progesterone and 17β-estradiol of black-rumped agouti (Dasyprocta prymnolopha) during the estrous cycle. The agouti is a game animal that have been raised in captivity for conservation and sustainability purposes. However, the management of wild animals in an intensive breeding system requires an assertive knowledge of its reproductive parameters, one of the most important features for production improvement. Besides, little information is available regarding changes in reproductive hormone profiles in agouti. The objective of this study was to evaluate the hormonal profile of progesterone and 17β-estradiol during the estrous cycle of the agouti (Dasyprocta prymnolopha). The hormones were analyzed by radioimmunoassay. Blood samples were collected without sedation twice a week. The concentrations of progesterone were as follows: proestrus 0.78+0.39ng/ml, estrus 2.83+2.34ng/ml, metestrus 1.49+1.24ng/ml, diestrus 3.71+1.48ng/ml. In the estrous phase, an increase in the progesterone level was observed during a period of 24h. The average 17 β-estradiol levels were as follows: proestrus 2 030.98+961.00pg/ml, estrus 1 910.56+650.54pg/ml, metestrus 1 724.83+767.28pg/ml, diestrus 1 939.94+725.29pg/ml. The current results suggest that the progesterone plasma concentration during the estrous cycle in the agouti has a similar increasing, stabilizing and decreasing pattern, as in domestic mammals. Agoutis have two phases of follicular development, as two periods of 17β-estradiol peaks were observed, the first one in the metestrus and the second during the proestrus. Spontaneous ovulation seems to occur after the progesterone peak, possibly indicating that this hormone is associated with the ovulatory process. A more detailed investigation is needed for better understanding of how progesterone influences ovulation. Studies on the involvement of progesterone in follicular rupture can be carried out, using steroid biosynthesis inhibitors and observing the effect of this hormone on ovarian activity of proteolytic enzymes in the follicular wall. Rev. Biol. Trop. 59 (1): 29-35. Epub 2011 March 01.


El conocimiento de los procesos reproductivos de especies de importancia económica local son indispensables para apoyar su producción en cautiverio y garantizar su manejo sostenible. El objetivo del presente trabajo fue evaluar los niveles hormonales de progesterona y 17β-estradiol durante el ciclo estral en agutí (Dasyprocta prymnolopha). La recolección de sangre se realizó dos veces por semana, sin sedación. Las hormonas fueron analizadas por radioinmunoanálisis. Los niveles de progesterona fueron los siguientes: proestro 0.78+0.39ng/ml, estro 2.83+2.34ng/ml, metaestro 1.49+1.24ng/ml y diestro 3.71+1.48ng/ml. En el estro se observó un aumento de los niveles de progesterona durante un periodo de 24h. Los niveles de 17 β-estradiol fueron los siguientes: proestro 2 030.98+961.00pg/ml, estro 1 910.56+650.54pg/ml, metaesto 1 724.83+767.28pg/ml y diestro 1 939.94+725.29pg/ ml. Los resultados encontrados sugieren que los niveles plasmáticos de progesterona durante el ciclo estral en agutí siguen un patrón de aumento, estabilización y diminución, tal como en los mamíferos domésticos. Agutí tienen dos etapas de desarrollo folicular, puesto que se observaron dos altos valores de 17β-estradiol, el primero en el metaestro y el segundo durante el proestro. La ovulación espontánea ocurre posiblemente después del aumento de la progesterona, indicando que esta hormona posiblemente está asociada con el proceso ovulatorio. Es necesario desarrollar un estudio más detallado para mejorar la comprensión del papel de la progesterona en la ovulación. Algunos estudios de la participación de la progesterona en la ruptura folicular se pueden realizar utilizando inhibidores de la biosíntesis de esteroides y observar el efecto de esta hormona sobre la actividad de las enzimas proteolíticas en la pared folicular.


Subject(s)
Animals , Female , Estradiol/blood , Estrous Cycle/blood , Ovulation/blood , Progesterone/blood , Rodentia/blood , Ovulation/physiology , Radioimmunoassay , Rodentia/physiology
7.
Pesqui. vet. bras ; 30(8): 670-675, ago. 2010. graf, mapas, tab
Article in Portuguese | LILACS | ID: lil-559902

ABSTRACT

O perfil hematológico sanguíneo foi determinado em três populações de Ctenomys lami, em áreas denominadas A e B, impactadas pela bovinocultura, e C, sem impacto antrópico, ambas no sul do Brasil. Sessenta e dois animais foram coletados ao total. Os valores de hematócrito (Ht), hemoglobina (Hb) e eritrócitos apresentaram diferenças significativas entre machos e fêmeas. Os valores médios de Ht e a Hb encontrados na espécie foram mais baixos em comparação com os de outras espécies de roedores subterrâneos, podendo estes valores estarem relacionados ao habitat de forrageio ou às características do solo. Também foram encontradas diferenças significativas nas médias de hemoglobina, CHCM e linfócitos em animais das áreas A e B em relação à área C. O valor da média dos hematócritos dos animais entre as áreas foi mais elevado nas áreas A e B, porém significativamente diferentes entre A e C. Algumas dessas alterações sugerem a relação dos valores encontrados com o estresse dos animais em relação a áreas impactadas. Variações significativas no VCM foram encontradas entre os animais das áreas A e C, e também nas plaquetas destes entre as áreas A e B. Não foram observados Corpúsculo de Kurloff no sangue dos animais analisados. Os valores hematológicos encontrados nesses espécimes de Ctenomys lami fornecem informações importantes sobre a espécie e podem ser úteis em outras pesquisas.


The hematological profile was determined in three populations of Ctenomys lami that inhabits three different areas nominated as A and B, affected by cattle production, and C, without human impact, all of them in southern Brazil, under the same geologic formation. Sixty two individuals were collected. The packed cell volume (PCV) values, hemoglobin (Hb) and red blood cell (RBC) count presents statistic significant differences between males and females. PCV and Hb values were lower in comparison with other subterranean rodents, which could be related to the food searching behavior or soil characteristic of the species. Significant statistic differences were found to for Hb, mean corpuscular hemoglobin concentration (MCHC) and lymphocytes between animals belonging to A and C areas. The PCV values were higher for animals from areas A and B, with significance only between A and C. Some of these alterations may suggest a modification on stress levels of the animals inhabiting areas A and B with anthropic alterations, or maybe just an inherited characteristic. Significant statistic differences were found either in mean corpuscular volume (MCV) between A and C areas, and platelets between A and B areas. No Kurloff cells were observed in the blood smear from analyzed individuals. The hematological values founded for Ctenomys lami are an important information for this species, which can be used for future research and management.


Subject(s)
Animals , Male , Female , Blood Physiological Phenomena , Refractometry/methods , Refractometry/veterinary , Rodentia/blood , Biopsy, Needle , Genetics, Behavioral , Staining and Labeling
8.
Braz. j. biol ; 67(3): 531-535, Aug. 2007. tab
Article in English | LILACS | ID: lil-470170

ABSTRACT

A study of blood parasites in small wild non-flying mammals was undertaken in three areas of the Atlantic Forest in Southeastern Brazil: Serra de Itatiaia, RJ, Serra da Bocaina, SP and Serra da Fartura, SP, from June 1999 to May 2001. A total of 450 animals (15 species) were captured in traps and it was observed in 15.5 percent of the blood smears the presence of Haemobartonella sp. and Babesia sp. in red blood cells. There was no statistically significant difference between parasited and non-parasited specimens regarding total plasma protein, packed cell volume and body weight, which strongly suggests that these specimens might be parasite reservoirs.


A presença de hemoparasitos em pequenos mamíferos silvestres não voadores foi pesquisada em animais de três áreas serranas do Sudeste brasileiro, pertencentes ao complexo da Serra do Mar e da Serra da Mantiqueira, nos Estados de São Paulo, Rio de Janeiro e Minas Gerais. Foram capturados 420 animais de 15 espécies, durante dois anos, dos quais, 15,5 por cento apresentaram Haemobartonella sp. e Babesia sp., observadas em lâmina de esfregaço sangüíneo no interior de suas hemácias. Os níveis de proteína total plasmática e de volume globular não apresentaram diferença estatisticamente significativa entre os indivíduos parasitados e não parasitados, assim como o peso corporal, o que sugere fortemente que esses animais possam ser reservatórios desses parasitos.


Subject(s)
Animals , Blood Cells/chemistry , Blood Proteins/analysis , Marsupialia/blood , Parasites/isolation & purification , Rodentia/blood , Brazil , Blood Cells/parasitology , Hematocrit , Marsupialia/parasitology , Parasites/classification , Rodentia/parasitology
9.
Rev. saúde pública ; 19(6): 521-30, dez. 1985. tab
Article in Portuguese | LILACS | ID: lil-27532

ABSTRACT

Roedores silvestres, nascidos em biotério, descendentes de Holochilus b. manus, capturados na regiäo da Baixada Maranhese, localizada na Pré-Amazônia, foram infectados experimentalmente com Schistosoma mansoni, procedente da mesma Regiäo, com o objetivo de verificar a influência da infecçäo sobre os níveis glicêmicos. Um grupo de roedores näo infectados tiveram, também, seus níveis glicêmicos detereminados, para o conhecimento da concentraçäo normal de glicose. O estudo procedeu distinguindo os animais, tanto os normais quanto os infectados, por sexo, regime alimentar e idade de infecçäo. A quantificaçäo da glicose sérica foi feita pelo método da Orto-Toluidina, após sangrias semanais pelo plexo oftálmico, sempre no mesmo horário. Os resultados mostraram que ocorreu elevaçäo de pesos corporais de todos os animais normais, durante suas maturaçöes, ao passo que, os animais infectados, tiveram seus pesos em decréscimo, durante a evoluçäo da infecçäo. Os níveis glicêmicos estudados nos animais mostraram que as fêmeas possuem nível mais baixo e estável do que os machos, independente de terem sido alimentados ou näo. Os animais infectados aos 30 dias de vida tiveram seus níveis glicêmicos em declínio à proporçäo que a infecçäo evoluía, provavelmente, devido ao acometimento dos órgäos, como baço, fígado e pâncreas; enquanto que, os animais infectados aos 40 dias de vida, tiveram seus níveis de glicose, durante as 8 semanas de infecçäo, sem diferença significativa entre eles. O número de vermes adultos recuperados nos animais infectados com 30 dias de vida foi maior do que o número encontrado nos roedores do grupo. Os dados informaram, também, que, a idade ideal para a infecçäo deste novo modelo experimental, deva ser a de 30 dias de vida, semelhante a outros, como camundongos


Subject(s)
Animals , Male , Female , Rodentia/blood , Schistosomiasis/blood , Blood Glucose/analysis , Schistosoma mansoni/growth & development , Schistosomiasis/parasitology , Body Weight , Brazil
10.
Rev. microbiol ; 16(4): 280-1, out.-dez. 1985. tab
Article in Portuguese | LILACS | ID: lil-31778

ABSTRACT

No período de 1983 a 1984 foram encontrados no foco pestoso da Serra dos Orgäos (Rio de Janeiro, Brasil) 6 roedores com títulos de anticorpos hemaglutinantes contra a fraçäo antigênica 1A da Yersinia pestis, >=1/16. A pesquisa do bacilo nos roedores e pulicídeos desse foco é recomendável


Subject(s)
Animals , Rodentia/blood , Yersinia pestis/isolation & purification , Brazil
11.
Rev. saúde pública ; 19(5): 431-7, out. 1985. tab
Article in Portuguese | LILACS | ID: lil-27106

ABSTRACT

Foram constituídos quatro grupos de roedores silvestres para a contagem de células sangüíneas periféricas, da seguinte forma: Grupo I - formado de animais normais, nascidos em biotério, com 30 dias de vida; Grupo II - formado de animais que foram capturados no campo e considerados näo infectados com S. mansoni, após ovohelmintoscopia das fezes, realizada durante 30 dias de observaçäo; Grupo III - animais capturados no campo, nautralmente infectados com o esquistossomo, e o Grupo IV - de animais nascidos em biotério, com 30 dias de vida, e infectados com 150 cercárias de S. mansoni, oriundas da Regiäo da Baixada Maranhense. Semanalmente, a partir da data da infecçäo, estes animais foram sangrados e tiveram suas células sangüíneas periféricas contadas global e especificamente. Os resultados mostraram que o número de hemácias e leucócitos por mm3 näo variou nos animais normais, tanto de campo como de biotério. No grupo de animais experimentalmente infectados, foi observado decréscimo do número de hemácias à proporçäo que a infecçäo evoluia. Comportamento oposto foi verificado com os leucócitos. Elevados níveis de eosinófilos só foram observados nos animais com infecçäo natural. Estes resultados foram discutidos com dados da literatura e considerados importantes para complementar as informaçöes sobre este hospedeiro natural do trematódeo, oferecido como modelo experimental do verme, e para sua própria história natural


Subject(s)
Animals , Rodentia/blood , Schistosomiasis/blood , Blood Cell Count , Schistosomiasis/immunology , Brazil , Eosinophils/immunology
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